Selected publications
We publish across a wide range of topics, from single-molecule and super-resolution microscopy to cell biology and neurodegeneration. For a comprehensive list of publications, visit our google scholar →.
PloS Biology
Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s disease
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Nature Communications
Co-aggregation with Apolipoprotein E modulates the function of Amyloid-ß in Alzheimer’s disease
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Angewandte Chemie
Single-Molecule Characterization and Super-Resolution Imaging of Alzheimer's Disease-Relevant Tau Aggregates in Human Samples
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Nature Protocols
Constructing a cost-efficient, high-throughput and high-quality single-molecule localization microscope for super-resolution imaging
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Molecular Cell
The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation
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Nature Methods
Quantitative analysis of super-resolved structures using ASAP
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PNAS
Dynamic label-free imaging of lipid nanodomains
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Team
We are a multi-disciplinary team of physicists, chemists, engineers, and software developers working together to develop new single-molecule instrumentation, software, and assays to rewire structural biology and diagnostics to decode dementia and other complex biological processes.
John Danial
PI
PDRA, Cambridge and Tuebingen; D.Phil. in Chemistry, Oxford
Siqi Liu
Software developer
BSc in Computer Science, St Andrews
Sabrina Keating
Programmer
BSc (enroute) in Physics, St Andrews
Funders
Our work is multi-disciplinary, and so is our funding. We are grateful to our funders who are investing in the developing of cutting-edge technologies and their application to some of the toughest biological and health problems.
Royal Society of Edinburgh
PI / £10,000 / Collaborative research grant (with Claire Durrant, Edinburgh and Juan Varela, St Andrews)
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University of St Andrews
PI / £125,000 / Start-up grant and master fund
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